Basic Information
VIS ID
TVIS44001690
Fusion event
HTLV-1-chr3 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
p21.33
Reference genome
GRCh37/hg19
Start
44086695/44045203 (Hg38)
End
44086695/44045203 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-12127/Upstream/4906937; hsa-let-7g/Downstream/69009;
Nearest TSS
ENST00000440867/Upstream/46054; ENST00000568686/Downstream/72096;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/22858, chr3-CpG: 48/Downstream/196544
Nearby gene
MIR138-1(+69009) ;
Nearest cancer related gene
MIR138-1(TSG, +69009) ;
Upstream sequence
ccagctgcacaggctgaccagttccctcacccatcactacctggccccaagggccaggcccccaccgaaacctttctgcacccatgttaagcattcctcc
Downstream sequence
acaacctcctgcaacgtgttcagaccctcgtgagagcaccctaggttgatgttctctgctcaccttctttttttctcactggtctgtgagctctttgaag
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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