Basic Information
VIS ID
TVIS44001693
Fusion event
HTLV-1-chr6 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
q12
Reference genome
End
64168767/63458862 (Hg38)
Orient
+
Location type
Intronic
Target gene
miRNAs that regulate target gene
hsa-mir-1273e ; hsa-mir-6516-5p ; hsa-mir-455-3p ; hsa-mir-6807-5p ; hsa-mir-486-3p ; hsa-mir-2467-3p ; hsa-mir-6499-3p ; hsa-mir-6086 ; hsa-mir-377-5p ; hsa-mir-6764-5p ; hsa-mir-1915-3p ; hsa-mir-6798-5p ; hsa-mir-4257 ; hsa-mir-6805-5p ; hsa-mir-7856-5p ; hsa-mir-4693-5p ; hsa-mir-1200 ; hsa-mir-1911-5p ; hsa-mir-544b ; hsa-mir-4324 ; hsa-mir-4793-5p ; hsa-mir-1278 ; hsa-mir-892a ; hsa-mir-4318 ; hsa-mir-2114-3p ; hsa-mir-6878-3p ; hsa-mir-6744-3p ; hsa-mir-4757-5p ; hsa-mir-4312 ; hsa-mir-3922-3p ; hsa-mir-6778-3p ; hsa-mir-3176 ; hsa-mir-422a ; hsa-mir-378i ; hsa-mir-378h ; hsa-mir-378f ; hsa-mir-378e ; hsa-mir-378d ; hsa-mir-378c ; hsa-mir-378b ; hsa-mir-378a-3p ; hsa-mir-1976 ; hsa-mir-150-5p ; hsa-mir-371a-5p ; hsa-mir-212-5p ; hsa-mir-8073 ; hsa-mir-221-5p ; hsa-mir-6747-3p ; hsa-mir-6727-3p ; hsa-mir-4722-3p ; hsa-mir-660-3p ; hsa-mir-5193 ; hsa-mir-186-3p ; hsa-mir-520h ; hsa-mir-520g-3p ; hsa-mir-512-3p ; hsa-mir-888-5p ; hsa-mir-520e ; hsa-mir-520d-3p ; hsa-mir-520c-3p ; hsa-mir-520b ; hsa-mir-520a-3p ; hsa-mir-373-3p ; hsa-mir-372-3p ; hsa-mir-302e ; hsa-mir-302d-3p ; hsa-mir-302c-3p ; hsa-mir-302b-3p ; hsa-mir-302a-3p ; hsa-mir-93-5p ; hsa-mir-526b-3p ; hsa-mir-519d-3p ; hsa-mir-20b-5p ; hsa-mir-20a-5p ; hsa-mir-17-5p ; hsa-mir-106b-5p ; hsa-mir-106a-5p ; hsa-mir-4659b-3p ; hsa-mir-4659a-3p ; hsa-mir-6875-3p ; hsa-mir-519e-5p ; hsa-mir-515-5p ; hsa-mir-5695 ; hsa-mir-519d-5p ; hsa-mir-1279 ; hsa-mir-6809-3p ; hsa-mir-6833-3p ; hsa-mir-4768-5p ; hsa-mir-6873-3p ; hsa-mir-6845-3p ; hsa-mir-136-5p
Nearest miRNA
hsa-mir-10398/Upstream/6068650; hsa-mir-10524/Downstream/7918098;
Nearby gene
PTP4A1(+113150) ;
Upstream sequence
AGTGTTAATGATTGCTAGGTTGTGACACTGAAATCAGTAAAACACGAATCAAATATTTACACATACCTTCCATGCAGTGTATTTTCCATCATGGGAAGGT
Downstream sequence
ATTGGGCAATGGAAAATTTCTCAAATACTTTTACTGGAAGAGACAAATTAGGCTCAGTTTTTTGTTACCATTATGTAAAGTTTGTAATAATGCTATGTGA
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
Curate