Basic Information
VIS ID
TVIS44001727
Fusion event
HTLV-1-LOC105370269 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr13
Cytoband
q22.3
Reference genome
GRCh37/hg19
Start
77537055/76962920 (Hg38)
End
77537055/76962920 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA13E
Target gene
LOC105370269
Nearest miRNA
hsa-mir-1297/Upstream/10744596; hsa-mir-1267/Downstream/735092;
Nearest TSS
ENST00000623511/Upstream/10443; ENST00000636405/Downstream/27740;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/75956, chr13-CpG: 27/Downstream/17208
Nearby gene
ACOD1(+4279) ;
Upstream sequence
ctggacaaataaatgttagtattggaccaagcattactataaatagtgtcactatgtaacgataaaaaattcaaatcaccagctaactgaaataatccta
Downstream sequence
accctacatgcacctaaATCATATTGAACTGCAAGAAGAAATCCatctaccaccatactgagagatttttaacattcctctcctattaattgatattcaa
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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