Basic Information
VIS ID
TVIS44001738
Fusion event
HTLV-1-NIPA2P3 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr21
Cytoband
q21.1
Reference genome
GRCh37/hg19
Start
21001488/19629174 (Hg38)
End
21001488/19629174 (Hg38)
Orient
+
Location type
Intronic
Target gene
NIPA2P3
Nearest miRNA
hsa-let-7c/Upstream/943010; hsa-mir-155/Downstream/3450110;
Nearest TSS
ENST00000624081/Upstream/327561; ENST00000486367/Downstream/270581;
Nearest CpG islands
None/Target, chr21-CpG: 261/Upstream/1383617, chr21-CpG: 89/Downstream/1367931
Nearby gene
MIR548XHG(No orient, 869358)
Upstream sequence
aaacacttgaatgtccaggcagaagtctgctgcagaggtggagcccttgtggataacctctgctagggcagtgtagaacagaaatgtggagttggaactc
Downstream sequence
ccacacagagtctccactggggcaccgtttagtggagctgtgagaagagagtcactgtcctccaggcctcagaatggtagatccactgatagcttgtacc
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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