Basic Information
VIS ID
TVIS44001748
Fusion event
HTLV-1-chr7 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
p22.3
Reference genome
GRCh37/hg19
Start
580088/540451 (Hg38)
End
580088/540451 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA7B
Nearest miRNA
hsa-mir-10399/Downstream/482482;
Nearest TSS
ENST00000635602/Upstream/20060; ENST00000453149/Downstream/21507;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/10046, chr7-CpG: 19/Downstream/1598
Nearby gene
PRKAR1B(-8746) ;
Upstream sequence
CAGAAAAATATAAACGTGGGCTCCTAGGAGCACCAGCACATGACCAGGACCTCGTCCTTCTAAAGCGTGTAAAGTTTGCTTTACTGTATTGACAGCAACA
Downstream sequence
ATAATCAGACCAAAAGCAAGATGACAAGACTCCTTCTCACTCGGGTAGTTCGGAGGAGCAAAGTGTGAGAGGCCCAGCGGGGCTGCAGCCTCAGCTCTGA
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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