VISDB Viral Integration Site DataBase

VIS ID

TVIS44001759

Fusion event

HTLV-1-SLC43A3 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

Adult T-cell leukemia (ATL)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr11

Cytoband

q12.1

Reference genome

Start

End

57186385/57418912 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-124-3p ; hsa-mir-574-5p ; hsa-mir-4455 ; hsa-mir-3688-5p ; hsa-mir-5010-3p ; hsa-mir-2113 ; hsa-mir-6885-3p ; hsa-mir-147a ; hsa-mir-6818-5p ; hsa-mir-6867-5p ; hsa-mir-5191 ; hsa-mir-5589-5p ; hsa-mir-4731-5p ; hsa-mir-6506-5p ; hsa-mir-619-5p ; hsa-mir-6083 ; hsa-mir-526b-5p ; hsa-mir-570-3p ; hsa-mir-4635 ; hsa-mir-215-3p ; hsa-mir-6773-3p ; hsa-mir-1248 ; hsa-mir-5088-3p ; hsa-mir-6793-3p ; hsa-mir-186-3p ; hsa-mir-6729-3p ; hsa-mir-3973 ; hsa-mir-6866-3p ; hsa-mir-188-5p ; hsa-mir-365b-3p ; hsa-mir-365a-3p ; hsa-mir-4662a-3p ; hsa-mir-5692a ; hsa-mir-559 ; hsa-mir-548y ; hsa-mir-548w ; hsa-mir-548o-5p ; hsa-mir-548j-5p ; hsa-mir-548i ; hsa-mir-548h-5p ; hsa-mir-548d-5p ; hsa-mir-548c-5p ; hsa-mir-548bb-5p ; hsa-mir-548b-5p ; hsa-mir-548ay-5p ; hsa-mir-548au-5p ; hsa-mir-548as-5p ; hsa-mir-548ar-5p ; hsa-mir-548aq-5p ; hsa-mir-548ap-5p ; hsa-mir-548am-5p ; hsa-mir-548ak ; hsa-mir-548ae-5p ; hsa-mir-548ad-5p ; hsa-mir-548ab ; hsa-mir-548a-5p ; hsa-mir-19a-5p ; hsa-mir-19b-1-5p ; hsa-mir-19b-2-5p ; hsa-mir-2052

Nearest miRNA

hsa-mir-129-2/Upstream/674931; hsa-let-7a-2/Downstream/222286;

Nearest TSS

Nearest CpG islands

None/Target, chr11-CpG: 30/Upstream/68811, chr11-CpG: 36/Downstream/7955

Upstream sequence

ccgggaggcggaggttgcagtgagccaagatcctgccaccgcactccagcctgggcaacagagcgagactctgtctcaaaaaaaaaaaaaggttaagata

Downstream sequence

gtaaattttatgttatgtatattttattgcatacaaaaaCATCAGCAGAAGAGGCAGGGGCTGGAACCCTGTTTTCTAAGGAGTCCTAGTACAAGCCATC