Basic Information
VIS ID
TVIS44001772
Fusion event
HTLV-1-ASIC2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
q11.2
Reference genome
GRCh37/hg19
Start
31705139/33378121 (Hg38)
End
31705139/33378121 (Hg38)
Orient
-
Location type
Intronic
Target gene
ASIC2
Nearest miRNA
hsa-mir-1180/Upstream/1027919; hsa-mir-10226/Downstream/3655624;
Nearest TSS
ENST00000595228/Upstream/85133; ENST00000585093/Downstream/155989;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/84674, chr17-CpG: 46/Downstream/661803
Upstream sequence
ACCCCCTGGTAGGCACAAGGTGGCACTGGATAGCACTCTCTGCTCTATGCATGGCATAGAggctgtgaagccagtagatctgggagtcaagtccacttac
Downstream sequence
agctgcgtgatcttgagcatgtcactttttccagtgcctcagtttccttctcactttctaaattttgaatgatagcttcatcagagattgttgtgatcat
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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