VISDB Viral Integration Site DataBase

VIS ID

TVIS44001785

Fusion event

HTLV-1-MYH9 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

Adult T-cell leukemia (ATL)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr22

Cytoband

q12.3

Reference genome

Start

End

36739124/36343079 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-124-3p ; hsa-mir-9-5p ; hsa-mir-1296-5p ; hsa-mir-877-3p ; hsa-mir-193b-3p ; hsa-mir-484 ; hsa-mir-324-3p ; hsa-mir-331-3p ; hsa-mir-149-5p ; hsa-mir-92a-3p ; hsa-let-7f-5p ; hsa-mir-4329 ; hsa-mir-4524a-3p ; hsa-mir-4538 ; hsa-mir-4453 ; hsa-mir-6507-5p ; hsa-mir-490-3p ; hsa-mir-5589-5p ; hsa-mir-4731-5p ; hsa-mir-150-5p ; hsa-mir-186-3p ; hsa-mir-520h ; hsa-mir-520g-3p ; hsa-mir-512-3p ; hsa-mir-520e ; hsa-mir-520d-3p ; hsa-mir-520c-3p ; hsa-mir-520b ; hsa-mir-520a-3p ; hsa-mir-373-3p ; hsa-mir-372-3p ; hsa-mir-302e ; hsa-mir-302d-3p ; hsa-mir-302c-3p ; hsa-mir-302b-3p ; hsa-mir-302a-3p ; hsa-mir-93-5p ; hsa-mir-526b-3p ; hsa-mir-519d-3p ; hsa-mir-20b-5p ; hsa-mir-20a-5p ; hsa-mir-17-5p ; hsa-mir-106b-5p ; hsa-mir-106a-5p ; hsa-mir-6821-5p ; hsa-mir-6513-5p ; hsa-mir-887-5p ; hsa-mir-3913-5p ; hsa-mir-3122 ; hsa-mir-450a-1-3p ; hsa-mir-6779-5p ; hsa-mir-6780a-5p ; hsa-mir-3689c ; hsa-mir-3689b-3p ; hsa-mir-3689a-3p ; hsa-mir-30b-3p ; hsa-mir-1273h-5p ; hsa-mir-6788-5p ; hsa-mir-30c-2-3p ; hsa-mir-30c-1-3p ; hsa-mir-7977 ; hsa-mir-6799-5p ; hsa-mir-6883-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-149-3p ; hsa-mir-7106-5p ; hsa-mir-24-3p ; hsa-mir-4284 ; hsa-mir-4267 ; hsa-mir-5196-5p ; hsa-mir-4747-5p ; hsa-mir-671-5p ; hsa-mir-338-3p ; hsa-mir-7157-5p ; hsa-mir-4310 ; hsa-mir-665 ; hsa-mir-1305 ; hsa-mir-7160-5p ; hsa-mir-4722-5p ; hsa-mir-1827 ; hsa-mir-15b-3p ; hsa-mir-4649-3p ; hsa-mir-4478 ; hsa-mir-4768-3p ; hsa-mir-4419b ; hsa-mir-3929 ; hsa-mir-940 ; hsa-mir-6893-5p ; hsa-mir-6808-5p ; hsa-mir-1193 ; hsa-mir-1233-5p ; hsa-mir-1294 ; hsa-mir-197-3p ; hsa-mir-2467-3p ; hsa-mir-3136-3p ; hsa-mir-3650 ; hsa-mir-370-5p ; hsa-mir-4257 ; hsa-mir-4316 ; hsa-mir-4481 ; hsa-mir-4688 ; hsa-mir-4745-5p ; hsa-mir-486-3p ; hsa-mir-5008-5p ; hsa-mir-518a-5p ; hsa-mir-527 ; hsa-mir-548aw ; hsa-mir-6743-5p ; hsa-mir-6778-5p ; hsa-mir-6814-5p ; hsa-mir-6818-5p ; hsa-mir-6867-5p ; hsa-mir-6871-5p ; hsa-mir-7155-3p ; hsa-mir-8070

Nearest miRNA

hsa-mir-1286/Upstream/56172; hsa-let-7a-3/Downstream/1501193;

Nearest TSS

Nearest CpG islands

None/Target, chr22-CpG: 279/Upstream/20364, chr22-CpG: 159/Downstream/43841

Nearest cancer related gene

MYH9(TSG, No orient, 0)

Upstream sequence

GTTCATGAAGCAGCCACCATCTGAGGGACTGCATGCACTACAGAGTCAACCCAGCCCCCTCCACCTGTGCCCTCTCCAGTCACTCCAAAACTGGGGATGG

Downstream sequence

ATCTTGTGGCTGAACCCAAAGACAGGGTCCACATAGGAACCAGTCATGAAGAGAAGGCTCTTCTCAGGCACTGGCCAAAGGCTATGGCACAGGGAATTTC