Basic Information
VIS ID
TVIS44001789
Fusion event
HTLV-1-chr3 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
q27.1
Reference genome
GRCh37/hg19
Start
183347033/183629245 (Hg38)
End
183347033/183629245 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
FRA3C
Nearest miRNA
hsa-let-7g/Upstream/7114094; hsa-mir-1224/Downstream/257555;
Nearest TSS
ENST00000440867/Upstream/73556; ENST00000481126/Downstream/6323;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/137090, chr3-CpG: 154/Downstream/6201
Nearby gene
KLHL24(+6378) ;
Upstream sequence
GAATAAAGAGTGTAGCTAGGCCTGGCATCACAATGGAGGAAGCATGCAGGTATGCCTTACCCCTCTGAAGTCAGAACTCGGGGCTCATGGTGATGACCAC
Downstream sequence
CACCTTATCTGCATCTAGATAGGTTTGGTCACACACAAAATCATGAGGCCACTGAGGCACCAATCGCCTGGCACCTCATCAACCTGTGAAGGACAGTTTT
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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