Basic Information
VIS ID
TVIS44001803
Fusion event
HTLV-1-GSAP integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
q11.23
Reference genome
GRCh37/hg19
Start
76983033/77353716 (Hg38)
End
76983033/77353716 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA7J
Target gene
GSAP
Nearest miRNA
hsa-mir-10525/Upstream/1438447; hsa-mir-10399/Downstream/14850299;
Nearest TSS
ENST00000635602/Upstream/21772; ENST00000608884/Downstream/1568;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/231639, chr7-CpG: 111/Downstream/61807
Upstream sequence
CATTCTCAGAAATCCACTGAATAATCTTTAAAAAGTCAGACAGAACTCTGTTGGTATTTAAATCTGCTCTCTGCCTCCACTACCAAAGAAGTACAAATAT
Downstream sequence
ACATGAATCTTTTGCATTCTATACCTATTTTAGAATTGCCTAAGAATATACTCACTTCTATACTATCTTCAAGATACATAATGCAATTCTGGGTAGGTAA
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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