Basic Information
VIS ID
TVIS44001805
Fusion event
HTLV-1-TSPAN33 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
q32.1
Reference genome
GRCh37/hg19
Start
128785458/129145618 (Hg38)
End
128785458/129145618 (Hg38)
Orient
-
Location type
Intronic
Target gene
TSPAN33
miRNAs that regulate target gene
hsa-mir-484 ; hsa-mir-10b-5p ; hsa-mir-10a-5p
Nearest miRNA
hsa-mir-10525/Upstream/937675; hsa-mir-10399/Downstream/624765;
Nearest TSS
ENST00000635602/Upstream/726; ENST00000496963/Downstream/16832;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/362, chr7-CpG: 41/Downstream/23630
Upstream sequence
TGGCATCATCTCTTCCTTTTGCAGGCCTCATCTACCCCCACCTCCACCCCCCCAAAGTCTAGGAAGAATGGCCTCCAGGTGCAGATGTCTTTCCCATCCC
Downstream sequence
AGCACTGCCCCAAACTTTGTCCCCTCCCTGCCACCCTTCTCAGGACCAGACTTCACCCCTGGAGCCTGGCAATCACCAGTGTCTTTAAACAGGACCCCGT
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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