Basic Information
VIS ID
TVIS44001807
Fusion event
HTLV-1-URGCP integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
p13
Reference genome
GRCh37/hg19
Start
43955426/43915827 (Hg38)
End
43955426/43915827 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA7D
Target gene
URGCP
miRNAs that regulate target gene
hsa-mir-877-3p ; hsa-mir-484 ; hsa-mir-548s ; hsa-mir-3926 ; hsa-mir-769-5p ; hsa-mir-4786-5p ; hsa-mir-3120-5p ; hsa-mir-3190-5p ; hsa-mir-5699-3p ; hsa-mir-4421 ; hsa-mir-339-5p ; hsa-mir-6849-3p ; hsa-mir-10b-5p ; hsa-mir-10a-5p ; hsa-mir-595 ; hsa-mir-6732-3p
Nearest miRNA
hsa-mir-1183/Upstream/764833; hsa-mir-10399/Downstream/135939;
Nearest TSS
ENST00000635602/Upstream/8758; ENST00000454428/Downstream/10511;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/8970, chr7-CpG: 74/Downstream/10380
Upstream sequence
gccaggcgcaatggctcatgcctgtaatcccagcactttgggaggctgaggcgggcagatcacctgaggtcaggagtttgagactagcctggccaacatg
Downstream sequence
gtgaaaccccgtctctactaaaaatacaaaaattagccgggcatggtggcatgcacctgtaatctcagctactcgggaggctgaggcaggagaatcactt
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
Curate