Basic Information
VIS ID
TVIS44001820
Fusion event
HTLV-1-ARHGAP29-AS1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p22.1
Reference genome
GRCh37/hg19
Start
94742246/94276690 (Hg38)
End
94742246/94276690 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA1D
Target gene
ARHGAP29-AS1
Nearest miRNA
hsa-mir-101-1/Upstream/429779; hsa-mir-11399/Downstream/267012;
Nearest TSS
ENST00000473358/Upstream/1622; ENST00000468860/Downstream/47879;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/28729, chr1-CpG: 101/Downstream/141279
Nearby gene
ARHGAP29(-38939) ;
Upstream sequence
ggcaacatggcaaaatcccatctctacaaaaaatacaaaaattagctgggcatggtggcgtgtgtctgtagtcccagctactcaggaggctgaggtggga
Downstream sequence
agatcacctgagccaaggagtttgaggctacagtgagctatgattgtgccactgcactccagcctgggtgacagagtgagaccctgtctcaaaaaaaaaa
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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