Basic Information
VIS ID
TVIS44001833
Fusion event
HTLV-1-HS3ST4 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr16
Cytoband
p12.1
Reference genome
GRCh37/hg19
Start
25774915/25763594 (Hg38)
End
25774915/25763594 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA16E
Target gene
HS3ST4
Nearest miRNA
hsa-mir-1225/Upstream/1560363; hsa-mir-11401/Downstream/261643;
Nearest TSS
ENST00000527434/Upstream/71568; ENST00000475436/Downstream/123152;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/70284, chr16-CpG: 34/Downstream/1346096
Upstream sequence
TGCATTTACCAACGATCACCAGGCACTGTGATGGGTGCTGGGATGTAATTGTGTGCAGTAATAGACACTGTCTAAGTTAAATATCTGAAGGAAGAAGAAG
Downstream sequence
GGTTAGCCATGTGAAGTGTGGCTAGGGGAGAGACATGGAATATTGCAGGCAGAGGGAAGGAATATGTGCGGGGCTCTGGAGCATGCATTCAGCTGGAAAG
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
Curate