Basic Information
VIS ID
TVIS44001838
Fusion event
HTLV-1-LOC100288728 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
p13.3
Reference genome
GRCh37/hg19
Start
3069887/3166593 (Hg38)
End
3069887/3166593 (Hg38)
Orient
+
Location type
Intronic
Target gene
LOC100288728
Nearest miRNA
hsa-mir-1253/Upstream/418411; hsa-mir-10226/Downstream/1803109;
Nearest TSS
ENST00000595228/Upstream/39012; ENST00000381951/Downstream/10342;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/117514, chr17-CpG: 81/Downstream/219475
Nearby gene
OR1A2(+30924) ;
Upstream sequence
ggagttcgagaccagcctgaccaacttggagagacccccatctccactgaaaatgcaaagttagccgggtgtggtgttgcatgcctgtggtcccagctac
Downstream sequence
tagggaggctgaggcagaagaatcacttgaccccaggaggcggaggttgtggtgagctgagatcacaccattgcactccagcctgggcaacaagagtgaa
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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