Basic Information
VIS ID
TVIS44001860
Fusion event
HTLV-1-AOAH integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
p14.2
Reference genome
GRCh37/hg19
Start
36588079/36548473 (Hg38)
End
36588079/36548473 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA7C
Target gene
AOAH
Nearest miRNA
hsa-mir-1183/Upstream/1607639; hsa-mir-10399/Downstream/370884;
Nearest TSS
ENST00000635602/Upstream/17789; ENST00000419326/Downstream/1783;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/158276, chr7-CpG: 136/Downstream/899278
Upstream sequence
cggggtttcaccatgttggccaggctggtctccaactcctgacctcaggtgatctgcccacctcggcctcccaaagtgctgggattataggtgtgagccc
Downstream sequence
ctgtgcccggccGTGCTTCTAAGATAGAGAAATTCAGCTGAACAGCAGGCTGCTATAATGGAGTGGAGTTGGTGAGGAGAGGGTGGGGAAGAGCCCAGAG
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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