VISDB Viral Integration Site DataBase

VIS ID

TVIS44001877

Fusion event

HTLV-1-NR6A1 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

Adult T-cell leukemia (ATL)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr9

Cytoband

q33.3

Reference genome

Start

End

127390863/124628584 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-421 ; hsa-mir-9-5p ; hsa-mir-181a-5p ; hsa-mir-218-5p ; hsa-mir-632 ; hsa-mir-4288 ; hsa-mir-4524b-5p ; hsa-mir-4524a-5p ; hsa-mir-346 ; hsa-mir-6508-3p ; hsa-mir-17-3p ; hsa-mir-1205 ; hsa-mir-1184 ; hsa-mir-646 ; hsa-mir-4257 ; hsa-mir-503-5p ; hsa-mir-6838-5p ; hsa-mir-497-5p ; hsa-mir-424-5p ; hsa-mir-195-5p ; hsa-mir-16-5p ; hsa-mir-15b-5p ; hsa-mir-15a-5p ; hsa-let-7e-5p ; hsa-mir-98-5p ; hsa-let-7c-5p ; hsa-mir-4500 ; hsa-let-7i-5p ; hsa-let-7a-5p ; hsa-mir-4458 ; hsa-let-7g-5p ; hsa-let-7d-5p ; hsa-let-7f-5p ; hsa-let-7b-5p ; hsa-mir-6864-5p ; hsa-mir-6126 ; hsa-mir-4440 ; hsa-mir-4493 ; hsa-mir-605-3p ; hsa-mir-4272 ; hsa-mir-5011-5p ; hsa-mir-15a-3p ; hsa-mir-3664-5p ; hsa-mir-1277-5p ; hsa-mir-4753-5p ; hsa-mir-4262 ; hsa-mir-181d-5p ; hsa-mir-181c-5p ; hsa-mir-181b-5p ; hsa-mir-1289 ; hsa-mir-196a-5p ; hsa-mir-196b-5p ; hsa-mir-1972 ; hsa-mir-2467-3p ; hsa-mir-3158-5p ; hsa-mir-3174 ; hsa-mir-3678-3p ; hsa-mir-3927-3p ; hsa-mir-4496 ; hsa-mir-4645-5p ; hsa-mir-4673 ; hsa-mir-4691-5p ; hsa-mir-4731-5p ; hsa-mir-4736 ; hsa-mir-486-3p ; hsa-mir-561-5p ; hsa-mir-6073 ; hsa-mir-654-3p ; hsa-mir-6721-5p ; hsa-mir-6830-5p ; hsa-mir-6831-5p ; hsa-mir-7844-5p ; hsa-mir-921

Nearest miRNA

hsa-let-7a-1/Upstream/1142962; hsa-mir-12126/Downstream/63858;

Nearest TSS

Nearest CpG islands

None/Target, chr9-CpG: 64/Upstream/123204, chr9-CpG: 144/Downstream/141177

Upstream sequence

aggcacatactaccacacccggctaattttttgtattttaatagagatggtgtttcaccatgttgaccaggatggtctcaatctcctgaccttgtgatcc

Downstream sequence

gtccgccttggctcccaaagtgctgggattacaggcatgagccaccacgtccagccTAtttttttttttttaaagagatggagtcttgctccgttgccca