Basic Information
VIS ID
TVIS44001878
Fusion event
HTLV-1-chr9 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr9
Cytoband
p24.1
Reference genome
GRCh37/hg19
Start
6402313/6402313 (Hg38)
End
6402313/6402313 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-101-2/Upstream/394409; hsa-let-7a-1/Downstream/12170993;
Nearest TSS
ENST00000422679/Upstream/73909; ENST00000381373/Downstream/10838;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/393984, chr9-CpG: 178/Downstream/10040
Nearby gene
UHRF2(+10838) ;
Nearest cancer related gene
UHRF2(TSG, +10838) ;
Upstream sequence
ttggaaggccgaggcgggcagatcatgaggtcaggagatcgagaccatcctggctaacacagtgaaacctcgtctctactaaaaatacaaagaattagcc
Downstream sequence
aggcgtggtgatgggcacctgtctgcagttccagctactcaggaggctgaggcaggagattggcatgaacctgggaggcggagcttgcagtgagctgaga
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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