Basic Information
VIS ID
TVIS44001893
Fusion event
HTLV-1-chr7 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
q31.2
Reference genome
GRCh37/hg19
Start
114989513/115349459 (Hg38)
End
114989513/115349459 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
FRA7G
Nearest miRNA
hsa-mir-10525/Upstream/696004; hsa-mir-10399/Downstream/1670752;
Nearest TSS
ENST00000635602/Upstream/118104; ENST00000489626/Downstream/326870;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/426684, chr7-CpG: 71/Downstream/860857
Nearby gene
LINC01392(No orient, 118104)
Upstream sequence
CTTGATTAATAGGAATTTTAAAAGAAAAAACTCACTTGGCCATTTAGAAATGTGTTTTGCTAGAAAAATGTAATTCTCTTTTGTAAAAGAATGCTGTTTC
Downstream sequence
ATTATTGCTTGTTTCATAACGCTTTTTCTCCCTTTTTTTGTTTTTATTACCATTAGAAAAAAAAATATGGCATTCTGCCTGTACTACAACTTTTGTCCAG
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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