Basic Information
VIS ID
TVIS44001901
Fusion event
HTLV-1-chr6 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
p22.3
Reference genome
GRCh37/hg19
Start
19892003/19891772 (Hg38)
End
19892003/19891772 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-3691/Upstream/1319892; hsa-mir-10398/Downstream/7255854;
Nearest TSS
ENST00000381078/Upstream/52692; ENST00000449143/Downstream/320315;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/52689, chr6-CpG: 83/Downstream/320265
Nearby gene
ID4(+49572) ;
Nearest cancer related gene
ID4(TSG, +49572) ;
Upstream sequence
TAACCAGCTTTCCCTAGCTCAGTTGAACACATCGTAAAATTATTTTCAGTAAGAAACCAGCTATACATTTTATGACTTATATAATAAAGAAACAAGAAAA
Downstream sequence
ATATGCACTTTATAAAATGATAATATGCTGTCATATGGAGCTTTTAAGTTAATGGGACATATAGGAAATGGTGCCGTTAACAAAAAGAAAAAAGAAAAAG
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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