VISDB Viral Integration Site DataBase

VIS ID

TVIS44001961

Fusion event

HTLV-1-FNDC3B integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

Adult T-cell leukemia (ATL)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr3

Cytoband

q26.31

Reference genome

Start

End

171771781/172053991 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-16-5p ; hsa-mir-143-3p ; hsa-mir-335-5p ; hsa-mir-155-5p ; hsa-mir-124-3p ; hsa-mir-1-3p ; hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-98-5p ; hsa-mir-30a-5p ; hsa-mir-26b-5p ; hsa-mir-378a-3p ; hsa-mir-92a-3p ; hsa-mir-25-3p ; hsa-mir-495-3p ; hsa-mir-5688 ; hsa-mir-32-5p ; hsa-mir-92b-3p ; hsa-mir-373-5p ; hsa-mir-616-5p ; hsa-mir-888-5p ; hsa-mir-4649-3p ; hsa-mir-371b-5p ; hsa-mir-181a-5p ; hsa-mir-181b-5p ; hsa-mir-181c-5p ; hsa-mir-181d-5p ; hsa-mir-218-5p ; hsa-mir-6516-5p ; hsa-mir-6874-5p ; hsa-mir-455-3p ; hsa-mir-6880-5p ; hsa-mir-6799-5p ; hsa-mir-3622b-5p ; hsa-mir-6851-5p ; hsa-mir-3689d ; hsa-mir-6500-5p ; hsa-mir-4633-3p ; hsa-mir-4327 ; hsa-mir-6499-3p ; hsa-mir-4722-5p ; hsa-mir-6134 ; hsa-mir-1827 ; hsa-mir-1247-3p ; hsa-mir-4768-3p ; hsa-mir-940 ; hsa-mir-6893-5p ; hsa-mir-6808-5p ; hsa-mir-5197-5p ; hsa-mir-9-3p ; hsa-mir-6835-3p ; hsa-mir-4422 ; hsa-mir-6513-5p ; hsa-mir-3656 ; hsa-mir-887-5p ; hsa-mir-3913-5p ; hsa-mir-3122 ; hsa-mir-450a-1-3p ; hsa-mir-6779-5p ; hsa-mir-6780a-5p ; hsa-mir-3689c ; hsa-mir-3689b-3p ; hsa-mir-3689a-3p ; hsa-mir-30b-3p ; hsa-mir-6788-5p ; hsa-mir-1273h-5p ; hsa-mir-30c-2-3p ; hsa-mir-7977 ; hsa-mir-30c-1-3p ; hsa-mir-675-5p ; hsa-mir-4466 ; hsa-mir-6848-5p ; hsa-mir-6846-5p ; hsa-mir-4283 ; hsa-mir-4437 ; hsa-mir-4284 ; hsa-mir-744-5p ; hsa-mir-4749-5p ; hsa-mir-4706 ; hsa-mir-342-3p ; hsa-mir-383-3p ; hsa-mir-1228-3p ; hsa-mir-1273a ; hsa-mir-4696 ; hsa-mir-6501-3p ; hsa-mir-451b ; hsa-mir-3145-5p ; hsa-mir-4432

Nearest miRNA

hsa-let-7g/Upstream/947232; hsa-mir-1224/Downstream/3315549;

Nearest TSS

Nearest CpG islands

None/Target, chr3-CpG: 148/Upstream/13057, chr3-CpG: 107/Downstream/393591

Nearest cancer related gene

FNDC3B(OG, No orient, 0)

Upstream sequence

CAGAGGATAAAAGTGTACTTCATAGAAAGTAATGTATAAGAAGCACAATGGAGTGAATGGGAAAAATTTGAGACAGTTGGTTAAGAAATGGTAGTGAAGC

Downstream sequence

TTTACCTTATTCGGACACTTTAAACACTCTATGAAAGGGAGTCCTTTTACTCACTGGTAAAACAGTTCTGTTCATCCGCAGTGCCTTTCATTTCAGTTAA