Basic Information
VIS ID
TVIS44001976
Fusion event
HTLV-1-LOC107984421 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
q13.4
Reference genome
GRCh37/hg19
Start
72523229/72812184 (Hg38)
End
72523229/72812184 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA11H
Target gene
LOC107984421
Nearest miRNA
hsa-mir-10392/Upstream/28592; hsa-let-7a-2/Downstream/1587053;
Nearest TSS
ENST00000527297/Upstream/18016; ENST00000451353/Downstream/2124;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/18102, chr11-CpG: 111/Downstream/1776
Nearby gene
ATG16L2(+2222) ;
Upstream sequence
actctgtctcaaaaaacaaaacaaaacaaaacaacaacaaaaccagcgatagtggcatgtgcctgtagtctcagctactcgggagactgaggtggaagaa
Downstream sequence
tcatttaatcccaggaggatgaggctgcagtgagccatgattgggccactgcactccagcctgggcaacagagagagaccctgtctcaaaaacaaaacag
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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