Basic Information
VIS ID
TVIS44001985
Fusion event
HTLV-1-LOC105377110 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
p14.2
Reference genome
GRCh37/hg19
Start
59172328/59186602 (Hg38)
End
59172328/59186602 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA3B
Target gene
LOC105377110
Nearest miRNA
hsa-let-7g/Upstream/3334008; hsa-mir-12124/Downstream/1431203;
Nearest TSS
ENST00000440867/Upstream/121452; ENST00000475527/Downstream/202102;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/136384, chr3-CpG: 48/Downstream/2064330
Nearby gene
C3orf67(No orient, 136613)
Upstream sequence
tctggcctctttcccactagaatgcaaactccatggaattgaaatcccaagtgttttggccttctttatatttctaccatcttaaacagtgtactaccac
Downstream sequence
acaacaagcactcagtaagtgcccattcaatgaatgaatATTGCTTAAGTACATTTTTTTGGTGCAAGTACTCTCTAAAATATTCATGTGAGAAATGGTG
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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