VISDB Viral Integration Site DataBase

VIS ID

TVIS44002003

Fusion event

HTLV-1-MSI2 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

Adult T-cell leukemia (ATL)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr17

Cytoband

q22

Reference genome

Start

End

55615361/57538000 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-155-5p ; hsa-mir-652-3p ; hsa-mir-484 ; hsa-mir-1273e ; hsa-mir-4766-5p ; hsa-mir-203a-3p ; hsa-mir-4282 ; hsa-mir-3163 ; hsa-mir-3688-3p ; hsa-mir-8076 ; hsa-mir-5580-3p ; hsa-mir-338-5p ; hsa-mir-3924 ; hsa-mir-3680-5p ; hsa-mir-4798-3p ; hsa-mir-2355-3p ; hsa-mir-676-3p ; hsa-mir-6500-5p ; hsa-mir-4633-3p ; hsa-mir-6502-5p ; hsa-mir-1301-5p ; hsa-mir-610 ; hsa-mir-708-5p ; hsa-mir-3139 ; hsa-mir-28-5p ; hsa-mir-190a-3p ; hsa-mir-202-3p ; hsa-mir-7162-3p ; hsa-mir-383-3p ; hsa-mir-5011-5p ; hsa-mir-410-3p ; hsa-mir-4678 ; hsa-mir-497-3p ; hsa-let-7c-5p ; hsa-let-7b-5p ; hsa-let-7d-5p ; hsa-let-7e-5p ; hsa-mir-4500 ; hsa-let-7f-5p ; hsa-let-7g-5p ; hsa-let-7i-5p ; hsa-let-7a-5p ; hsa-mir-4458 ; hsa-mir-98-5p ; hsa-mir-3165 ; hsa-mir-3689d ; hsa-mir-3911 ; hsa-mir-3975 ; hsa-mir-4302 ; hsa-mir-4519 ; hsa-mir-4695-5p ; hsa-mir-6134 ; hsa-mir-6499-3p ; hsa-mir-6851-5p ; hsa-mir-6880-5p ; hsa-mir-6894-5p ; hsa-mir-7154-3p ; hsa-mir-765 ; hsa-mir-766-5p ; hsa-mir-7847-3p ; hsa-mir-8071

Nearest miRNA

hsa-mir-10226/Upstream/646645; hsa-mir-1250/Downstream/793232;

Nearest TSS

Nearest CpG islands

None/Target, chr17-CpG: 26/Upstream/280935, chr17-CpG: 60/Downstream/311851

Upstream sequence

TCTTTCCTTTGGAATAAAAGCCCTGGCACCAAAAGGGTGGTGACCTAATAGGTCTTCCTGCCTCCCCCTGCTGTGGCCCACGGAAGCAGAAAGGGAGTGG

Downstream sequence

GCTCAGGGTCAGCAACTTCACTGACCCAGAAGTGGTTTTTTTGTAGAGAGGGACAATGAATCTTTTGTTTGGTCCTGTTCCCATAGAGGCCCAGGCTCTG