Basic Information
VIS ID
TVIS44002032
Fusion event
HTLV-1-OTOP3 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
q25.1
Reference genome
GRCh37/hg19
Start
72944233/74948138 (Hg38)
End
72944233/74948138 (Hg38)
Orient
-
Location type
Intronic
Target gene
OTOP3
Nearest miRNA
hsa-mir-10226/Upstream/199439; hsa-mir-1250/Downstream/457931;
Nearest TSS
ENST00000595228/Upstream/12336; ENST00000577295/Downstream/6834;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/11632, chr17-CpG: 101/Downstream/23934
Upstream sequence
gcactgaaAACATACCTGAGAAATGAAACCTCTGGTCCAGGCAGAGAATAAATTGGCTCTaaagtgcattaggagctcagcaaaggaactgtgggcctgc
Downstream sequence
atagccaaggaaggcttcatgaagttttgatctgagccttgaggaaggggtagaatttggacaggaaggtaggagggggcagggggtcataactagcaga
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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