Basic Information
VIS ID
TVIS44002066
Fusion event
HTLV-1-chr13 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr13
Cytoband
q31.1
Reference genome
GRCh37/hg19
Start
81143675/80569540 (Hg38)
End
81143675/80569540 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-1297/Upstream/2871424; hsa-mir-1267/Downstream/7049125;
Nearest TSS
ENST00000623511/Upstream/228589; ENST00000456588/Downstream/474130;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/226454, chr13-CpG: 31/Downstream/85372
Nearby gene
SPRY2(-228589) ;
Nearest cancer related gene
SPRY2(TSG, -228589) ;
Upstream sequence
CATATGTGAGTGTCATACTTTAGATGCTTCCATTTCTTCCTTTAAGAGACCCTGAGTTTTCCTAGTTTGGTACCTTTCTCCTTCTGTTGCCCATATCTGT
Downstream sequence
AATTCCATTTTTACATTTTGAAATCTCCTTCACCTTTCAAGACTCATAAATAACCAGGTCTTTGCAAATTTTTTTCTTCATCTCTCTATTGAAATAATTT
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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