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TVIS44002081
Basic Information
VIS ID
TVIS44002081
Fusion event
HTLV-1-FOXP1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
p13
Reference genome
GRCh37/hg19
Start
71625057/71575906 (Hg38)
End
71625057/71575906 (Hg38)
Orient
+
Location type
Intronic
Target gene
FOXP1
miRNAs that regulate target gene
hsa-mir-1-3p
;
hsa-mir-122-5p
;
hsa-mir-34a-5p
;
hsa-mir-335-5p
;
hsa-mir-33a-5p
;
hsa-mir-22-3p
;
hsa-mir-1229-3p
;
hsa-mir-320a
;
hsa-mir-100-5p
;
hsa-mir-9-5p
;
hsa-mir-512-5p
;
hsa-mir-218-5p
;
hsa-mir-4276
;
hsa-mir-105-5p
;
hsa-mir-7853-5p
;
hsa-mir-578
;
hsa-mir-548aw
;
hsa-mir-526b-5p
;
hsa-mir-1468-3p
;
hsa-mir-548x-5p
;
hsa-mir-548g-5p
;
hsa-mir-548f-5p
;
hsa-mir-548aj-5p
;
hsa-mir-1181
;
hsa-mir-5195-5p
;
hsa-mir-4480
;
hsa-mir-577
;
hsa-mir-497-3p
;
hsa-mir-1277-5p
;
hsa-mir-607
;
hsa-mir-3671
;
hsa-mir-190a-3p
;
hsa-mir-223-5p
;
hsa-mir-511-3p
;
hsa-mir-5011-5p
;
hsa-let-7c-3p
;
hsa-mir-486-5p
;
hsa-mir-8485
;
hsa-mir-649
;
hsa-mir-335-3p
;
hsa-mir-30e-3p
;
hsa-mir-30d-3p
;
hsa-mir-30a-3p
;
hsa-mir-6882-3p
;
hsa-mir-27b-5p
;
hsa-mir-152-3p
;
hsa-mir-148b-3p
;
hsa-mir-148a-3p
;
hsa-mir-556-5p
;
hsa-mir-512-3p
;
hsa-mir-208b-5p
;
hsa-mir-208a-5p
;
hsa-mir-367-5p
;
hsa-mir-4639-5p
;
hsa-mir-4517
;
hsa-mir-19b-3p
;
hsa-mir-19a-3p
;
hsa-mir-6507-3p
;
hsa-mir-1264
;
hsa-mir-431-5p
;
hsa-mir-561-3p
;
hsa-mir-6821-5p
Nearest miRNA
hsa-let-7g/Upstream/33817; hsa-mir-12124/Downstream/3638570;
Nearest TSS
ENST00000440867/Upstream/8043;
ENST00000604491/Downstream/5815;
Nearest CpG islands
None/Target,
chr3-CpG: 148/Upstream/510236
,
chr3-CpG: 155/Downstream/5516
Nearest cancer related gene
FOXP1
(TSG, No orient, 0)
Upstream sequence
AAGCAGGGAACCTGGAGCAGAGAAAGTCACATTATGACTCAATTGCACAGCTGGGAGGGAGAAAGGACACCTCGGAAATTCAGTTTGATGCTAGAAATAT
Downstream sequence
TCTTCAGTGTCCTAGTAAACAAAGTGAATCACAAAATTAGCTAAAATCAGAGCATCTGGTAAAATGTGGATGTCCACCTGACTTACAAGTAATAAATAAA
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
Sample Information
×
Sample name
ATL11-CR3
Sample type
Nontumor
Age
27
Gender
Male
CpG Island Information
×
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