Basic Information
VIS ID
TVIS44002093
Fusion event
HTLV-1-LOC105376000 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr9
Cytoband
p21.2
Reference genome
GRCh37/hg19
Start
26720253/26720255 (Hg38)
End
26720253/26720255 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA9C
Target gene
LOC105376000
Nearest miRNA
hsa-mir-101-2/Upstream/5208070; hsa-let-7a-1/Downstream/2143371;
Nearest TSS
ENST00000422679/Upstream/653580; ENST00000523363/Downstream/26698;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/1041569, chr9-CpG: 69/Downstream/172035
Nearby gene
CAAP1(No orient, 120430)
Upstream sequence
ttttaatgaagataggagctcaaggaaataacctccctaacatcagtaaggattttggatcaggattccaaattaagtcCAGGTTTTGCCAAAATGGAAG
Downstream sequence
GTGATGTCATTGTCTGTTGTTACATTGGACATTTCCTTTTCACTCTCAACAGAAGACTTTAAGAAGTTTGATCCCCACTCAGACATCACCAGATACTGAC
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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