Basic Information
VIS ID
TVIS44002105
Fusion event
HTLV-1-chr13 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr13
Cytoband
q14.3
Reference genome
GRCh37/hg19
Start
53584294/53010159 (Hg38)
End
53584294/53010159 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-15a/Upstream/200019; hsa-mir-1267/Downstream/1301813;
Nearest TSS
ENST00000623511/Upstream/161518; ENST00000219022/Downstream/18600;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/158299, chr13-CpG: 217/Downstream/189970
Nearby gene
OLFM4(+18582) ;
Nearest cancer related gene
OLFM4(TSG, +18582) ;
Upstream sequence
aaaggcatttacaatctatgggagactggcagggccaaggtgttgtctttttgtttaccactctacacctgggccccccacagtgcccagaacatggggg
Downstream sequence
aacttaataaatGGATGGACCTAGGCATTTCCACAACTCTGCAGAGCATAAGTGCTAAAAGTGAGAACTAGCAGGAACCTAAGTGAGTTTCTCAGATTAG
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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