VISDB Viral Integration Site DataBase

VIS ID

TVIS44002112

Fusion event

HTLV-1-ATXN7L3 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

Adult T-cell leukemia (ATL)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr17

Cytoband

q21.31

Reference genome

Start

End

42273235/44195867 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-16-5p ; hsa-mir-766-3p ; hsa-mir-615-3p ; hsa-mir-193b-3p ; hsa-mir-484 ; hsa-mir-125a-5p ; hsa-mir-222-3p ; hsa-mir-6779-3p ; hsa-mir-3667-3p ; hsa-mir-412-3p ; hsa-mir-6754-3p ; hsa-mir-6756-3p ; hsa-mir-607 ; hsa-mir-6783-3p ; hsa-mir-1343-3p ; hsa-mir-3671 ; hsa-mir-6721-5p ; hsa-mir-486-3p ; hsa-mir-6716-5p ; hsa-mir-4763-3p ; hsa-mir-1207-5p ; hsa-mir-202-3p ; hsa-mir-570-3p ; hsa-mir-6742-3p ; hsa-mir-6852-5p ; hsa-mir-939-3p ; hsa-mir-4422 ; hsa-let-7g-5p ; hsa-mir-4500 ; hsa-let-7b-5p ; hsa-let-7c-5p ; hsa-mir-4458 ; hsa-let-7d-5p ; hsa-let-7i-5p ; hsa-let-7e-5p ; hsa-let-7f-5p ; hsa-let-7a-5p ; hsa-mir-98-5p ; hsa-mir-6835-3p ; hsa-mir-7111-5p ; hsa-mir-6870-5p ; hsa-mir-5698 ; hsa-mir-4723-5p ; hsa-mir-6825-5p ; hsa-mir-7106-5p ; hsa-mir-765 ; hsa-mir-6722-3p ; hsa-mir-1909-3p ; hsa-mir-1827 ; hsa-mir-4784 ; hsa-mir-3150b-3p ; hsa-mir-6791-5p ; hsa-mir-4292 ; hsa-mir-6798-5p ; hsa-mir-6754-5p ; hsa-mir-4441 ; hsa-mir-4270 ; hsa-mir-211-3p ; hsa-mir-6794-5p ; hsa-mir-4716-3p ; hsa-mir-4756-5p ; hsa-mir-4739 ; hsa-mir-1321 ; hsa-mir-940 ; hsa-mir-6893-5p ; hsa-mir-6808-5p ; hsa-mir-6749-3p ; hsa-mir-6792-3p ; hsa-mir-4691-5p ; hsa-mir-2355-5p ; hsa-mir-3157-5p ; hsa-mir-7155-3p ; hsa-mir-3136-3p ; hsa-mir-5581-5p ; hsa-mir-4297 ; hsa-mir-4685-3p ; hsa-mir-4287 ; hsa-mir-5088-3p ; hsa-mir-5685 ; hsa-mir-4690-3p ; hsa-mir-3614-3p ; hsa-mir-1915-3p ; hsa-mir-361-3p ; hsa-mir-514a-3p ; hsa-mir-514b-3p ; hsa-mir-6764-5p

Nearest miRNA

hsa-mir-1180/Upstream/750982; hsa-mir-10226/Downstream/11904;

Nearest TSS

Nearest CpG islands

None/Target, chr17-CpG: 26/Upstream/8431, chr17-CpG: 147/Downstream/3454

Upstream sequence

GAGAGCAAGCATGAGGGGCGGCCCATACTCACCTTAAAAGGATCCGAATTGCTAAGTTCCCCTGAAGAAGAAAAAAGAAGGGGAAGGGTGTTTGATGCAG

Downstream sequence

AGGTACAGACAGAGAACCCTGAAAATAACCAGAGAGGAAGTGGGGGTGACAGAAGGATCACAGGCCCTCCCTCAATTCCCCTATCCCCGGGCCCCACCTC