Basic Information
VIS ID
TVIS44002113
Fusion event
HTLV-1-chr18 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr18
Cytoband
q22.3
Reference genome
GRCh37/hg19
Start
69709428/72042193 (Hg38)
End
69709428/72042193 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-1-2/Upstream/4960507; hsa-mir-548av/Downstream/811128;
Nearest TSS
ENST00000575820/Upstream/97616; ENST00000578967/Downstream/498105;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/1611333, chr18-CpG: 225/Downstream/499546
Upstream sequence
ATGTTATATGTAATATATATAATGTTGCTCCAAACTCCATAACTAAGACAACAATCAATACTATTAAATTGCTGCTAAAATAAATTTAAAGCAATGCTGA
Downstream sequence
AGTTATAAAACTATAGTTTAGGAAGGTTTTAAGCACCAAGAGAATAAAGCGTGATGAGATAAATTCTCTATACTGACATAGTATTTCAAAAACTTATTTT
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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