Basic Information
VIS ID
TVIS44002118
Fusion event
HTLV-1-ARHGAP25 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
p13.3
Reference genome
GRCh37/hg19
Start
68953134/68726002 (Hg38)
End
68953134/68726002 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA2S ; FRA2E
Target gene
ARHGAP25
Nearest miRNA
hsa-mir-1301/Upstream/2367674; hsa-mir-10b/Downstream/377680;
Nearest TSS
ENST00000437798/Upstream/46040; ENST00000463061/Downstream/8833;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/70560, chr2-CpG: 84/Downstream/286949
Nearby gene
ARHGAP25(+8779) ;
Upstream sequence
tggctcattctcaacctggcttaggtctttactcaaatgtcacctattctgtgaaatgtcaccttcgctgtccaactatttaaaaatgcaatctccctcc
Downstream sequence
cctctcccctcaatctgacatttctttcaccccttcccgtagcactttttctttttctccacagcccttaccaccatctaacacgttacatttatttcac
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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