Basic Information
VIS ID
TVIS44002172
Fusion event
HTLV-1-ANO4 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
q23.1
Reference genome
GRCh37/hg19
Start
101467309/101073531 (Hg38)
End
101467309/101073531 (Hg38)
Orient
+
Location type
Intronic
Target gene
ANO4
miRNAs that regulate target gene
hsa-mir-378c
Nearest miRNA
hsa-let-7i/Upstream/883582; hsa-mir-1178/Downstream/2856894;
Nearest TSS
ENST00000382841/Upstream/25543; ENST00000551998/Downstream/136876;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/355687, chr12-CpG: 62/Downstream/136078
Upstream sequence
ggcagggagagggatagcgttaggagaaatacctaatgtaaatgacgagttaatgggtgcagcaaaccaacatggcacatgtatacatatgtaacaaatc
Downstream sequence
tgcacgttgtgcacatataccctagaacttaaagtataataataataataataataataataataaaagaaaataataGGGTGTGGCCTGAAGAACATTC
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
Curate