Basic Information
VIS ID
TVIS44002177
Fusion event
HTLV-1-GUCY1B2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr13
Cytoband
q14.3
Reference genome
GRCh37/hg19
Start
51579423/51005287 (Hg38)
End
51579423/51005287 (Hg38)
Orient
+
Location type
ncRNA_intronic
Target gene
GUCY1B2
Nearest miRNA
hsa-mir-15a/Upstream/956086; hsa-mir-1267/Downstream/343280;
Nearest TSS
ENST00000623511/Upstream/57223; ENST00000614264/Downstream/105922;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/94832, chr13-CpG: 86/Downstream/216694
Upstream sequence
AAGGGAGAGGGGACTGGGAAATGCACAGAAGCATGAAAAGGGTTGGGATCCTTCCTTCCTGggaccacatatatgtttgtgcagttttctctacatggag
Downstream sequence
gcacctggccaaggggttcagggtgaggactgacctcagtccacacagaggttgccattttcctctatgataagccatgtctgggggctgtcgaccccat
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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