Basic Information
VIS ID
TVIS44002191
Fusion event
HTLV-1-chr2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q22.1
Reference genome
GRCh37/hg19
Start
138686317/137928747 (Hg38)
End
138686317/137928747 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA2S
Nearest miRNA
hsa-mir-128-1/Upstream/2263269; hsa-mir-10b/Downstream/2657879;
Nearest TSS
ENST00000437798/Upstream/286504; ENST00000280096/Downstream/35273;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/1162621, chr2-CpG: 71/Downstream/572716
Nearby gene
LOC101928273(No orient, 815)
Upstream sequence
agttatgctgccacagaccaagaaatgccaagacccatcagaagctgaaagaggcaaggaaggattgcagctttccaaggaagggtgtccctactaacac
Downstream sequence
accttgattttggacttctgaccttcacaacagtgagagaatacattcttgttgtttaagccacccagtttgtggtactttgttatggtggcctcaggaa
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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