Basic Information
VIS ID
TVIS44002203
Fusion event
HTLV-1-chr4 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr4
Cytoband
p16.1
Reference genome
GRCh37/hg19
Start
7751783/7750056 (Hg38)
End
7751783/7750056 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA4A
Nearest miRNA
hsa-mir-378d-1/Upstream/289938; hsa-mir-12113/Downstream/255245;
Nearest TSS
ENST00000502981/Upstream/15776; ENST00000608442/Downstream/4034;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/85436, chr4-CpG: 19/Downstream/50408
Nearby gene
AFAP1-AS1(+4034) ;
Upstream sequence
tgagggtcctccacggttctgaattgccagaagacaactgtagagggatatggagaggaaaagtctgtggctcagtttcagtctctgttactcacttgta
Downstream sequence
aagcaaacagaaggatttgtaggtatttgaaaatgtgtgattcatgcacctttcaagaaagaaaaaaaatcctcaaagatatccccttatccatcaagcg
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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