Basic Information
VIS ID
TVIS44002207
Fusion event
HTLV-1-P4HA2-AS1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr5
Cytoband
q31.1
Reference genome
GRCh37/hg19
Start
131524424/132188731 (Hg38)
End
131524424/132188731 (Hg38)
Orient
+
Location type
ncRNA_intronic
Fragile sites / regions
FRA5C
Target gene
P4HA2-AS1
Nearest miRNA
hsa-mir-10397/Upstream/2791584; hsa-mir-103a-1/Downstream/29118;
Nearest TSS
ENST00000502646/Upstream/3855; ENST00000463615/Downstream/4837;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/176648, chr5-CpG: 100/Downstream/38670
Upstream sequence
ttgggctgagtctggtactgagaagacaagaattagagttgaggaactgccagtggaaacagatccagtgaacacactaggctctcaattagaaaatcct
Downstream sequence
ggaggactacatcctataaggggggaaataagggtaaaccagagatagagtcttaagaaaactaccacccagtcttaattttaagtcagctcagatcctt
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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