Basic Information
VIS ID
TVIS44002218
Fusion event
HTLV-1-chr7 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
q36.1
Reference genome
GRCh37/hg19
Start
148185752/148488660 (Hg38)
End
148185752/148488660 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA7I
Nearest miRNA
hsa-mir-10399/Upstream/1110539; hsa-mir-153-2/Downstream/2749761;
Nearest TSS
ENST00000635602/Upstream/73912; ENST00000307003/Downstream/14798;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/148904, chr7-CpG: 200/Downstream/209678
Nearby gene
CNTNAP2(+67664) ;
Nearest cancer related gene
CNTNAP2(TSG, +67664) ;
Upstream sequence
ttgtccaggctggagtgcagtggcacgatctcggctcactgcaagctccgcctcctgggttcacgccattctcctgcctcagcctcctaagtagctggga
Downstream sequence
ctacaggtgcctgccatcacacctggctaatttttctatttctagtagagacggggtttcaccatgttagccaggatggtctcgatttcctgaccttgtg
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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