Basic Information
VIS ID
TVIS44002220
Fusion event
HTLV-1-LOC102724874 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr8
Cytoband
q21.13
Reference genome
GRCh37/hg19
Start
78379014/77466778 (Hg38)
End
78379014/77466778 (Hg38)
Orient
+
Location type
ncRNA_intronic
Target gene
LOC102724874
Nearest miRNA
hsa-mir-124-1/Upstream/499928; hsa-mir-10400/Downstream/1865410;
Nearest TSS
ENST00000518652/Upstream/16081; ENST00000521879/Downstream/681323;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/465957, chr8-CpG: 46/Downstream/1049420
Upstream sequence
AATCACTCATTATTAAGTTCATAATACCTGATTTTATCAAATTATGCATATACAAAAGGTGTCCATGCCTATTTTGTGGACAAGAACAAAGTAAGTGAAA
Downstream sequence
ACTCCCATGATAGGTAATGCTCATGTGTGATATAAAATGCACCTCCAACTTGCTGAAGCTTTCTCTTCCTTCATTGATGCGGTTTCTGTAATTCCACATA
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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