Basic Information
VIS ID
TVIS44002231
Fusion event
HTLV-1-chr1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p21.2
Reference genome
GRCh37/hg19
Start
100282359/99816803 (Hg38)
End
100282359/99816803 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
FRA1E
Nearest miRNA
hsa-mir-101-1/Upstream/1770632; hsa-mir-11399/Downstream/464438;
Nearest TSS
ENST00000473358/Upstream/50172; ENST00000477753/Downstream/33281;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/552024, chr1-CpG: 63/Downstream/33061
Nearby gene
AGL(+33281) ;
Upstream sequence
GCCTTGGCCACTGACCAACTGATGAGGCTGAGTtggtggctctctttagagtgcggagaactaagtgcctctgggcctcacatctgtactttattctggg
Downstream sequence
acaagaggaaaactctcactcagcaaccaccgtgttacaCCTCGGATCCTGTTACACTGAGTTTAAcccaggagaccagccaggtgaagtccctcatgac
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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