Basic Information
VIS ID
TVIS44002233
Fusion event
HTLV-1-C2CD4D-AS1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
q21.3
Reference genome
GRCh37/hg19
Start
151814319/151841843 (Hg38)
End
151814319/151841843 (Hg38)
Orient
-
Location type
ncRNA_exonic
Fragile sites / regions
FRA1F
Target gene
C2CD4D-AS1
Nearest miRNA
hsa-mir-101-1/Upstream/295952; hsa-mir-1182/Downstream/1847862;
Nearest TSS
ENST00000473358/Upstream/1286; ENST00000434182/Downstream/34;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/1794, chr1-CpG: 66/Downstream/67444
Upstream sequence
agtcaagtgaagcaatgggagtggagatggaacaaagaaatctgcaattggttgtgatcaattagttgtaaacactactgcacttggaccaacctcttcc
Downstream sequence
ttttcctGACTGCTTAGGAAGGATGGAATGTATTTCCTTCCTTCTGGGAGTGTTTGAATGAAGATTAGACTCTCCTTGACCATGAATGAAGAGCAACCAG
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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