Basic Information
VIS ID
TVIS44002253
Fusion event
HTLV-1-chr11 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
q13.3
Reference genome
GRCh37/hg19
Start
69598391/69783623 (Hg38)
End
69598391/69783623 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
FRA11H ; FRA11A
Nearest miRNA
hsa-mir-10392/Upstream/700365; hsa-let-7a-2/Downstream/500332;
Nearest TSS
ENST00000527297/Upstream/8220; ENST00000534086/Downstream/33927;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/7845, chr11-CpG: 32/Downstream/26717
Nearby gene
FGF4(-8220) ;
Nearest cancer related gene
FGF4(OG, -8220) ;
Upstream sequence
aaagtgctgggattacaggcatgagtcactgcgctgggccTTCTGTTACTTCTAATTAATTTATTAATTGACTTTTGGGGgagacacagttttactgtgc
Downstream sequence
ccccccaggctggagtgcagggctgtgatcttggctcactgcaacctccgcctttcagattcaagcaattctcctgcctcagcctcctgagtggctggga
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
Curate