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TVIS44002273
Basic Information
VIS ID
TVIS44002273
Fusion event
HTLV-1-CD276 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr15
Cytoband
q24.1
Reference genome
GRCh37/hg19
Start
73980435/73688094 (Hg38)
End
73980435/73688094 (Hg38)
Orient
-
Location type
Intronic
Target gene
CD276
miRNAs that regulate target gene
hsa-mir-29a-3p
;
hsa-mir-29c-3p
;
hsa-mir-335-5p
;
hsa-mir-1301-3p
;
hsa-mir-421
;
hsa-mir-92a-3p
;
hsa-mir-28-5p
;
hsa-let-7a-5p
;
hsa-mir-1260b
;
hsa-mir-187-3p
;
hsa-mir-29b-3p
;
hsa-mir-328-5p
;
hsa-mir-4323
;
hsa-mir-4447
;
hsa-mir-4472
;
hsa-mir-4651
;
hsa-mir-486-3p
;
hsa-mir-541-3p
;
hsa-mir-5682
;
hsa-mir-608
;
hsa-mir-654-5p
;
hsa-mir-6751-5p
;
hsa-mir-6752-5p
;
hsa-mir-6756-5p
;
hsa-mir-6766-5p
;
hsa-mir-6769a-5p
;
hsa-mir-6769b-5p
;
hsa-mir-6795-5p
;
hsa-mir-6803-5p
;
hsa-mir-6835-5p
;
hsa-mir-6842-5p
;
hsa-mir-6871-3p
;
hsa-mir-6885-5p
;
hsa-mir-6887-5p
;
hsa-mir-7109-5p
;
hsa-mir-7110-5p
;
hsa-mir-7153-3p
;
hsa-mir-767-5p
;
hsa-mir-92a-2-5p
Nearest miRNA
hsa-mir-10393/Upstream/388115; hsa-mir-11181/Downstream/723263;
Nearest TSS
ENST00000557528/Upstream/3088;
ENST00000557951/Downstream/11546;
Nearest CpG islands
None/Target,
chr15-CpG: 55/Upstream/3180
,
chr15-CpG: 136/Downstream/64126
Upstream sequence
TAGGAGCTCATGGTACTTGGAACTGTGACCAAGCATCTGCGAAGAGGAAGGGGCCCAGGACCACTAGAATGAGTCAGAGCCAGAGATGGAGTCGAGTTGT
Downstream sequence
GCATTTGCTACTTTGGAGCTGGGGCACTGATAGGGCTCTAGGTGAAAAGTAGGGATACAGAAGGAGTAATGGTCCCAGAGGCCCAGATGTGTGGCCTGAC
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
Sample Information
×
Sample name
ATL11-CR3
Sample type
Nontumor
Age
27
Gender
Male
CpG Island Information
×
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