Basic Information
VIS ID
TVIS44002305
Fusion event
HTLV-1-LOC105374834 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
p11.2
Reference genome
GRCh37/hg19
Start
83759296/83532172 (Hg38)
End
83759296/83532172 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA2S ; FRA2L
Target gene
LOC105374834
Nearest miRNA
hsa-mir-1285-2/Upstream/3665589; hsa-mir-10b/Downstream/2251428;
Nearest TSS
ENST00000437798/Upstream/9358; ENST00000440495/Downstream/782936;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/2064615, chr2-CpG: 27/Downstream/758418
Nearby gene
DHFRP3(+674403) ;
Upstream sequence
cttattttggttaagctaGTAGAGTCAGGCTTCTATTAAGTGCAATCCCAATTCAAAATGTGATTTTAGGTAAGTCATTTCATATGCTAACTTATCCAGA
Downstream sequence
TTCTAATTTAATCACTTTGCCATTGCATAAGATAATTTCTAAGATCACTAGTTCTATCACAGGTTTTCCTTTAAAATAAAAACACTATTATCTAAACTAA
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
Curate