Basic Information
VIS ID
TVIS44002316
Fusion event
HTLV-1-ULK4 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
p22.1
Reference genome
GRCh37/hg19
Start
41567934/41526443 (Hg38)
End
41567934/41526443 (Hg38)
Orient
-
Location type
Intronic
Target gene
ULK4
Nearest miRNA
hsa-mir-12127/Upstream/2388177; hsa-let-7g/Downstream/2587769;
Nearest TSS
ENST00000440867/Upstream/248292; ENST00000418790/Downstream/328468;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/326303, chr3-CpG: 17/Downstream/364674
Upstream sequence
GCATAGAATGAGATGGGGCCTCCATTTGTGCCTGTTACTTAAACACTCAAGAGACCCATGTGGCCACAGCTAAGGCAATTCAGCCATAAGGTCCTGTCTA
Downstream sequence
GTTCTGCCTAATGTGCTTCCTGAGATCACTTTCTTAAGCTTAAAGGCAAGACCAGAGATGACAGAAATGGTCTATCAGCATGGTCTCTCCTGCAGCACTC
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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