Basic Information
VIS ID
TVIS44002332
Fusion event
HTLV-1-chr5 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr5
Cytoband
q14.2
Reference genome
GRCh37/hg19
Start
82348289/83052470 (Hg38)
End
82348289/83052470 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-10397/Upstream/212246; hsa-mir-103a-1/Downstream/4062409;
Nearest TSS
ENST00000502646/Upstream/1506; ENST00000509268/Downstream/9505;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/773994, chr5-CpG: 23/Downstream/24813
Nearby gene
TMEM167A(-376) ;
Upstream sequence
TATAAATTGGCTGAATAATCTGACTGATGGACAATGCTCACAAACAGATTTTAGACAGAAAATAATAGTTACTTGCCAGAATGTTTGGGCATCTGAAGGC
Downstream sequence
TCCCAGTTGAGGACAAGGTTGAAAATAACTCAGTAATTGATAACTGTCACTTTCACTCAGAATCGGATTTCCACCATCTCTGGGAAAATTAAAGACTTCA
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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