Basic Information
VIS ID
TVIS44002341
Fusion event
HTLV-1-LOC105377899 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
q16.1
Reference genome
GRCh37/hg19
Start
94335313/93625595 (Hg38)
End
94335313/93625595 (Hg38)
Orient
-
Location type
Intronic
Target gene
LOC105377899
Nearest miRNA
hsa-mir-10398/Upstream/2103858; hsa-mir-1202/Downstream/4398936;
Nearest TSS
ENST00000381078/Upstream/206048; ENST00000424678/Downstream/261305;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/205636, chr6-CpG: 69/Downstream/1951770
Nearby gene
TSG1(+81488) ;
Upstream sequence
TAATAACATTAAGAGGTTGGTGAAAATTATATAATGGGCACTTGGGAAACCATTTTTAAAGGTCATTTCTAATTATATTTTAATGGGTGCAGATATATGT
Downstream sequence
ATATATAATGTGTGTGTGCATGTGTGTTAGATTAGTTCAGATGAAAGCCAGCTACAAGAAAAAGCTGTTTTTTAAGATGCATTTTTAATTTGTCTGTGTG
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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