Basic Information
VIS ID
TVIS44002360
Fusion event
HTLV-1-chr8 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr8
Cytoband
q24.3
Reference genome
GRCh37/hg19
Start
142723253/141713153 (Hg38)
End
142723253/141713153 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
FRA8D
Nearest miRNA
hsa-mir-1204/Upstream/980500; hsa-mir-10400/Downstream/73089;
Nearest TSS
ENST00000518652/Upstream/198456; ENST00000562989/Downstream/376674;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/92785, chr8-CpG: 20/Downstream/10752
Nearby gene
MIR1302-7(-144350) ;
Upstream sequence
CCCTAGGGTCTGAAGCAGGAAGGAGCTGCCCAGCCCAGTGAGCTGGAACCCGCAGGACTCTGGAGGCATGGCTTGGTCCCTCTGCAGAAGCTCAGAAAGG
Downstream sequence
GAGGTGTCATCTGCCCCAGCAGAACTGAGGGCCCGGGAAGTGGGAGGCCCACTCCTGCTGCTGATGGCTCCAGAGATAATCTCCCCCGGATATTGACAAC
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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