Basic Information
VIS ID
TVIS44002366
Fusion event
HTLV-1-LURAP1L-AS1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr9
Cytoband
p23
Reference genome
GRCh37/hg19
Start
12735847/12735848 (Hg38)
End
12735847/12735848 (Hg38)
Orient
-
Location type
ncRNA_intronic
Target gene
LURAP1L-AS1
Nearest miRNA
hsa-mir-101-2/Upstream/6727944; hsa-let-7a-1/Downstream/5837458;
Nearest TSS
ENST00000422679/Upstream/28177; ENST00000489107/Downstream/39173;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/1117260, chr9-CpG: 28/Downstream/39639
Upstream sequence
TGAGGTCATTTTATTAGATGGAACAAGCAGCAAACCAATCTGGGTCAGGACAGGATAAGAGATACTAAGGGTTTTTCCTTTCTCAAGATATTCTAGGTAA
Downstream sequence
AATTGCATTCAGGATGCAGGAAGGTACAAAAATACTTCTAGGGGATTTCCTAAATGCGGTTATTGAGAACCAATTTTAATTTAAAAAGCAGCAGCATTTG
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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