Basic Information
VIS ID
TVIS44002372
Fusion event
HTLV-1-UHMK1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
q23.3
Reference genome
End
162474147/162504357 (Hg38)
Orient
+
Location type
Intronic
Target gene
miRNAs that regulate target gene
hsa-mir-1-3p ; hsa-mir-124-3p ; hsa-mir-335-5p ; hsa-mir-148b-3p ; hsa-mir-9-5p ; hsa-mir-503-5p ; hsa-mir-185-5p ; hsa-mir-151a-3p ; hsa-mir-4463 ; hsa-mir-4499 ; hsa-mir-4742-3p ; hsa-mir-9500 ; hsa-mir-548c-3p ; hsa-mir-4305 ; hsa-mir-4696 ; hsa-mir-4711-5p ; hsa-mir-3183 ; hsa-mir-4723-3p ; hsa-mir-6769b-3p ; hsa-mir-6865-3p ; hsa-mir-6892-3p ; hsa-mir-5689 ; hsa-mir-1277-5p ; hsa-mir-1910-3p ; hsa-mir-3714 ; hsa-mir-6511a-5p ; hsa-mir-200b-5p ; hsa-mir-200a-5p ; hsa-mir-548an ; hsa-mir-4775 ; hsa-mir-298 ; hsa-mir-190a-3p ; hsa-mir-5011-5p ; hsa-mir-410-3p ; hsa-mir-3606-5p ; hsa-mir-4528 ; hsa-mir-944 ; hsa-mir-32-3p ; hsa-mir-4678 ; hsa-mir-5584-5p ; hsa-mir-6716-5p ; hsa-mir-6750-5p ; hsa-mir-6822-5p ; hsa-mir-382-3p ; hsa-mir-2909 ; hsa-mir-3162-5p ; hsa-mir-494-3p ; hsa-mir-4788 ; hsa-mir-496 ; hsa-mir-4764-5p ; hsa-mir-105-3p ; hsa-mir-6854-5p ; hsa-mir-28-3p ; hsa-mir-6511b-5p ; hsa-mir-136-3p ; hsa-mir-3166 ; hsa-mir-1324 ; hsa-mir-6726-3p ; hsa-mir-3692-3p ; hsa-mir-194-5p ; hsa-mir-6733-3p ; hsa-mir-5688 ; hsa-mir-495-3p ; hsa-mir-139-5p ; hsa-mir-142-5p ; hsa-mir-216b-3p ; hsa-mir-340-5p ; hsa-mir-345-5p ; hsa-mir-372-5p ; hsa-mir-377-3p ; hsa-mir-4684-5p ; hsa-mir-4768-5p ; hsa-mir-513a-5p ; hsa-mir-520f-5p ; hsa-mir-548a-5p ; hsa-mir-548ab ; hsa-mir-548ad-5p ; hsa-mir-548ae-5p ; hsa-mir-548ak ; hsa-mir-548am-5p ; hsa-mir-548ap-5p ; hsa-mir-548aq-5p ; hsa-mir-548ar-5p ; hsa-mir-548as-5p ; hsa-mir-548au-5p ; hsa-mir-548av-5p ; hsa-mir-548ay-5p ; hsa-mir-548b-5p ; hsa-mir-548bb-5p ; hsa-mir-548c-5p ; hsa-mir-548d-5p ; hsa-mir-548h-5p ; hsa-mir-548i ; hsa-mir-548j-5p ; hsa-mir-548k ; hsa-mir-548l ; hsa-mir-548o-5p ; hsa-mir-548w ; hsa-mir-548y ; hsa-mir-5590-3p ; hsa-mir-559 ; hsa-mir-6757-3p ; hsa-mir-6809-3p ; hsa-mir-6833-3p ; hsa-mir-8054 ; hsa-mir-888-5p ; hsa-mir-186-5p ; hsa-mir-3121-5p ; hsa-mir-3133 ; hsa-mir-3149 ; hsa-mir-3157-3p ; hsa-mir-3713 ; hsa-mir-4733-5p ; hsa-mir-651-5p ; hsa-mir-6886-3p ; hsa-mir-874-3p ; hsa-mir-938
Nearest miRNA
hsa-mir-101-1/Upstream/161717; hsa-mir-1182/Downstream/3403564;
Upstream sequence
GGTCTGGGGACAGATACAGTTTTTCTGATATCTGAATAGATCCGAAAACAATAGATATTTTGAAAATACAAATGTGTAcagtcgtgtcatttaacagtag
Downstream sequence
ggatctgttgtgagaaatatgtcattaggtgattttgccatgctgacatcatatagtacttacataaatgtaaatgatacagacttctgcccacacctag
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
Curate