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TVIS44002372
Basic Information
VIS ID
TVIS44002372
Fusion event
HTLV-1-UHMK1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
q23.3
Reference genome
GRCh37/hg19
Start
162474147/162504357 (Hg38)
End
162474147/162504357 (Hg38)
Orient
+
Location type
Intronic
Target gene
UHMK1
miRNAs that regulate target gene
hsa-mir-1-3p
;
hsa-mir-124-3p
;
hsa-mir-335-5p
;
hsa-mir-148b-3p
;
hsa-mir-9-5p
;
hsa-mir-503-5p
;
hsa-mir-185-5p
;
hsa-mir-151a-3p
;
hsa-mir-4463
;
hsa-mir-4499
;
hsa-mir-4742-3p
;
hsa-mir-9500
;
hsa-mir-548c-3p
;
hsa-mir-4305
;
hsa-mir-4696
;
hsa-mir-4711-5p
;
hsa-mir-3183
;
hsa-mir-4723-3p
;
hsa-mir-6769b-3p
;
hsa-mir-6865-3p
;
hsa-mir-6892-3p
;
hsa-mir-5689
;
hsa-mir-1277-5p
;
hsa-mir-1910-3p
;
hsa-mir-3714
;
hsa-mir-6511a-5p
;
hsa-mir-200b-5p
;
hsa-mir-200a-5p
;
hsa-mir-548an
;
hsa-mir-4775
;
hsa-mir-298
;
hsa-mir-190a-3p
;
hsa-mir-5011-5p
;
hsa-mir-410-3p
;
hsa-mir-3606-5p
;
hsa-mir-4528
;
hsa-mir-944
;
hsa-mir-32-3p
;
hsa-mir-4678
;
hsa-mir-5584-5p
;
hsa-mir-6716-5p
;
hsa-mir-6750-5p
;
hsa-mir-6822-5p
;
hsa-mir-382-3p
;
hsa-mir-2909
;
hsa-mir-3162-5p
;
hsa-mir-494-3p
;
hsa-mir-4788
;
hsa-mir-496
;
hsa-mir-4764-5p
;
hsa-mir-105-3p
;
hsa-mir-6854-5p
;
hsa-mir-28-3p
;
hsa-mir-6511b-5p
;
hsa-mir-136-3p
;
hsa-mir-3166
;
hsa-mir-1324
;
hsa-mir-6726-3p
;
hsa-mir-3692-3p
;
hsa-mir-194-5p
;
hsa-mir-6733-3p
;
hsa-mir-5688
;
hsa-mir-495-3p
;
hsa-mir-139-5p
;
hsa-mir-142-5p
;
hsa-mir-216b-3p
;
hsa-mir-340-5p
;
hsa-mir-345-5p
;
hsa-mir-372-5p
;
hsa-mir-377-3p
;
hsa-mir-4684-5p
;
hsa-mir-4768-5p
;
hsa-mir-513a-5p
;
hsa-mir-520f-5p
;
hsa-mir-548a-5p
;
hsa-mir-548ab
;
hsa-mir-548ad-5p
;
hsa-mir-548ae-5p
;
hsa-mir-548ak
;
hsa-mir-548am-5p
;
hsa-mir-548ap-5p
;
hsa-mir-548aq-5p
;
hsa-mir-548ar-5p
;
hsa-mir-548as-5p
;
hsa-mir-548au-5p
;
hsa-mir-548av-5p
;
hsa-mir-548ay-5p
;
hsa-mir-548b-5p
;
hsa-mir-548bb-5p
;
hsa-mir-548c-5p
;
hsa-mir-548d-5p
;
hsa-mir-548h-5p
;
hsa-mir-548i
;
hsa-mir-548j-5p
;
hsa-mir-548k
;
hsa-mir-548l
;
hsa-mir-548o-5p
;
hsa-mir-548w
;
hsa-mir-548y
;
hsa-mir-5590-3p
;
hsa-mir-559
;
hsa-mir-6757-3p
;
hsa-mir-6809-3p
;
hsa-mir-6833-3p
;
hsa-mir-8054
;
hsa-mir-888-5p
;
hsa-mir-186-5p
;
hsa-mir-3121-5p
;
hsa-mir-3133
;
hsa-mir-3149
;
hsa-mir-3157-3p
;
hsa-mir-3713
;
hsa-mir-4733-5p
;
hsa-mir-651-5p
;
hsa-mir-6886-3p
;
hsa-mir-874-3p
;
hsa-mir-938
Nearest miRNA
hsa-mir-101-1/Upstream/161717; hsa-mir-1182/Downstream/3403564;
Nearest TSS
ENST00000473358/Upstream/6272;
ENST00000476240/Downstream/56951;
Nearest CpG islands
None/Target,
chr1-CpG: 111/Upstream/6120
,
chr1-CpG: 95/Downstream/56709
Upstream sequence
GGTCTGGGGACAGATACAGTTTTTCTGATATCTGAATAGATCCGAAAACAATAGATATTTTGAAAATACAAATGTGTAcagtcgtgtcatttaacagtag
Downstream sequence
ggatctgttgtgagaaatatgtcattaggtgattttgccatgctgacatcatatagtacttacataaatgtaaatgatacagacttctgcccacacctag
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
Sample Information
×
Sample name
ATL11-CR3
Sample type
Nontumor
Age
27
Gender
Male
CpG Island Information
×
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